Skip to main content

Scientists just used CRISPR to encode a GIF into the DNA of a virus

bacteria in a petri dish
Is there a movie you love enough to have an image from it tattooed onto your body? Soon you may be able to go one step further and have the entirety of one of its scenes spliced into your DNA. After all, what better way to show your love for pre-Phantom Menace George Lucas than to have the climactic Death Star meridian trench sequence from Star Wars permanently etched into your genetic makeup, courtesy of gene editing tech CRISPR?

A variation of this was achieved recently by Harvard scientists, who have demonstrated how E. coli bacteria is capable of storing images and movies in its DNA.

“We wanted to test whether the CRISPR-Cas system in bacteria could be used to capture complex information with a time component in living bacteria,” Dr. Seth Shipman, a neuroscientist at Harvard who led the experiment, told Digital Trends. “To do that, we encoded images and a movie into DNA and delivered them to cells expressing two proteins from the CRISPR system: Cas1 and Cas2. The reason we care about this is that we want to create living molecular recorders, cells that can capture new information and store that information in their genome, this is a way that we could pilot such a system.”

The movie footage the researchers used isn’t quite the Star Wars: A New Hope climax, but it’s no less an iconic part of cinema history. It’s a 36 x 26-pixel GIF displaying a galloping horse filmed by Eadweard Muybridge in one of the first motion pictures ever shot — way back in 1878. Using DNA sequencing tech, Shipman and colleagues were able to both store the data and then later reassemble it with 90 percent accuracy. Doing this not only showed that DNA is capable of storing the images, but also of doing so in the correct order.

So is there any real-world use for this? “Not quite yet, but hopefully on the near horizon,” Shipman said. “We want to use this technology to create cells that can record biological or environmental signals.” As to what’s next for the project, he noted that the “next step is to hook the input of this system to a biological system, then we might be able to use it to gather information that we don’t currently have.”

A research paper describing the work was published this week in the journal Nature.

Editors' Recommendations

Luke Dormehl
I'm a UK-based tech writer covering Cool Tech at Digital Trends. I've also written for Fast Company, Wired, the Guardian…
The best portable power stations
EcoFlow DELTA 2 on table at campsite for quick charging.

Affordable and efficient portable power is a necessity these days, keeping our electronic devices operational while on the go. But there are literally dozens of options to choose from, making it abundantly difficult to decide which mobile charging solution is best for you. We've sorted through countless portable power options and came up with six of the best portable power stations to keep your smartphones, tablets, laptops, and other gadgets functioning while living off the grid.
The best overall: Jackery Explorer 1000

Jackery has been a mainstay in the portable power market for several years, and today, the company continues to set the standard. With three AC outlets, two USB-A, and two USB-C plugs, you'll have plenty of options for keeping your gadgets charged.

Read more
CES 2023: HD Hyundai’s Avikus is an A.I. for autonomous boat and marine navigation
Demonstration of NeuBoat level 2 autonomous navigation system at the Fort Lauderdale International Boat Show

This content was produced in partnership with HD Hyundai.
Autonomous vehicle navigation technology is certainly nothing new and has been in the works for the better part of a decade at this point. But one of the most common forms we see and hear about is the type used to control steering in road-based vehicles. That's not the only place where technology can make a huge difference. Autonomous driving systems can offer incredible benefits to boats and marine vehicles, too, which is precisely why HD Hyundai has unveiled its Avikus AI technology -- for marine and watercraft vehicles.

More recently, HD Hyundai participated in the Fort Lauderdale International Boat Show, to demo its NeuBoat level 2 autonomous navigation system for recreational boats. The name mashes together the words "neuron" and "boat" and is quite fitting since the Avikus' A.I. navigation tech is a core component of the solution, it will handle self-recognition, real-time decisions, and controls when on the water. Of course, there are a lot of things happening behind the scenes with HD Hyundai's autonomous navigation solution, which we'll dive into below -- HD Hyundai will also be introducing more about the tech at CES 2023.

Read more
This AI cloned my voice using just three minutes of audio
acapela group voice cloning ad

There's a scene in Mission Impossible 3 that you might recall. In it, our hero Ethan Hunt (Tom Cruise) tackles the movie's villain, holds him at gunpoint, and forces him to read a bizarre series of sentences aloud.

"The pleasure of Busby's company is what I most enjoy," he reluctantly reads. "He put a tack on Miss Yancy's chair, and she called him a horrible boy. At the end of the month, he was flinging two kittens across the width of the room ..."

Read more